The weather in Matagalpa tends to be cool year-round, with average temperatures ranging from 20°C to 25°C. The dry season typically runs from December to April, while the rainy season lasts from May to November. Rain is more frequent during the rainy season, keeping the vegetation around Matagalpa lush and fertile throughout the year.

Matagalpa is a special destination for coffee enthusiasts because it is one of Nicaragua's premier coffee producers. Matagalpa coffee is renowned for its high quality, grown on the fertile mountain slopes and in a climate that is conducive to coffee cultivation.

Visitors can tour coffee plantations scattered around the city, learning about the coffee processing from planting to brewing, and of course, tasting coffee directly from its source. This experience not only provides deep insights into the coffee-making process but also delights the taste buds with its distinctive and enjoyable coffee flavors.

Matagalpa hosts various fascinating cultural events, one of which is the San Jerónimo Festival celebrated with great pomp every August. This festival is a religious and cultural celebration adorned with traditional costume parades, folk dances, and music performances that enliven the city's atmosphere. Besides the San Jerónimo Festival, other celebrations include music festivals, art exhibitions, and traditional markets that add local color and warmly welcome tourists.

To reach Matagalpa from Augusto C. Sandino International Airport in Managua, there are several transportation options available. A common method is to take a taxi or rent a car. The overland journey from Managua Airport to Matagalpa typically takes about 2-3 hours depending on traffic conditions.

Another option is to use public bus services available at the Managua bus terminal heading to Matagalpa. Some hotels or travel agencies also offer pre-arranged transfer services for your travel convenience.

One of the must-try local delicacies in Matagalpa is "quesillo." Quesillo is a traditional Nicaraguan snack consisting of corn tortilla wrapped around soft white cheese, complemented with onions and topped with a splash of lime juice. It is refreshing and perfect as a light snack or appetizer.